Tracking the relevant researches of CADD drug development against COVID-19
Andrographolide (HMPL-004) is a botanical product extracted from a herb that occurs naturally in China. The herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and other inflammatory and infectious diseases. [DrugBank]
Tumor necrosis factor (Humans); Interleukin-1 beta (Humans); Interleukin-6 (Humans); Nuclear factor NF-kappa-B p100 subunit (Humans); Nuclear factor NF-kappa-B p105 subunit (Humans) [DrugBank]
Not Available [DrugBank]
Tips: Click on the link to jump to the 'SwissTargetPrediction' webserver. Select the species of 'Homo sapiens', and then paste the SMILES of Andrographolide in the SMILES input box.
Tips: Click on the link to jump to the 'CB-Dock' webserver. Upload the structure file of target predicted by 'SwissTargetPrediction' and the 2D/3D structure file of Andrographolide to perform blind docking.